SUPT7L

Across TCGA patient cohorts, SUPT7L mutation is significantly associated with the RNA expression of many other genes, with 1,819 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUPT7L-associated genes across cancer lineages are ACTR3BP3, RNU4-87P, and RNU6-7. Each is linked with SUPT7L in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT7L-to-partner and partner-to-SUPT7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ACTR3BP3 grouped by SUPT7L-low versus SUPT7L-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT7L→partner) and Y-score (partner→SUPT7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ACTR3BP3 →	+0.054	+8.471	<.001	.005	3	2
COAD	RNU4-87P →	+0.943	+4.537	<.001	.006	3	2
COAD	RNU6-7 →	+0.355	+4.173	.009	.003	3	2
COAD	TRAJ50 →	+0.705	+4.308	<.001	.009	3	2
COAD	RN7SL741P →	+0.388	+4.537	<.001	.006	3	2
UCEC	ALDOA →	+0.458	+2.724	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,819 associations by consensus.

ACTR3BP3 by SUPT7L expression — BRCA

Explore this box plot interactively →