SUPT7L

Across TCGA cell cohorts, SUPT7L mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SUPT7L-associated genes across cancer lineages are KRTAP4-4, MSGN1, and TAFA1. Each is linked with SUPT7L in more than 1 cancer types. Because this analysis shows association rather than direction, both SUPT7L-to-partner and partner-to-SUPT7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP4-4 grouped by SUPT7L-low versus SUPT7L-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT7L→partner) and Y-score (partner→SUPT7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KRTAP4-4 →	+0.024	+4.643	<.001	.005	3	1
LARGE_INTESTINE	MSGN1 →	+0.082	+3.345	<.001	.007	3	1
LARGE_INTESTINE	TAFA1 →	+0.274	+3.688	<.001	.002	3	1
LARGE_INTESTINE	C14orf180 →	+0.176	+3.155	<.001	.008	3	1
LARGE_INTESTINE	LRRC3C →	+0.333	+3.658	<.001	.005	3	1
CNS	IFNA4 →	+0.215	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

KRTAP4-4 by SUPT7L expression — BLOOD_Lymphoma

Explore this box plot interactively →