SUPT20H

Across TCGA cell cohorts, SUPT20H mutation is significantly associated with the mutation status of many other genes, with 2,153 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SUPT20H-associated genes across cancer lineages are PIK3R2, BTAF1, and MYBPC3. Each is linked with SUPT20H in more than 2 cancer types. Because this analysis shows association rather than direction, both SUPT20H-to-partner and partner-to-SUPT20H results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIK3R2 grouped by SUPT20H-low versus SUPT20H-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUPT20H→partner) and Y-score (partner→SUPT20H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	PIK3R2 →	+5.000	+4.044	.008	.008	1	3
LARGE_INTESTINE	BTAF1 →	+2.321	+2.919	.003	.003	1	3
STOMACH	MYBPC3 →	+4.807	+4.807	.008	.008	1	3
BLOOD_Leukemia	KIF1A →	+3.560	+5.209	<.001	<.001	1	3
BLOOD_Leukemia	LRP4 →	+2.975	+3.794	.006	.006	1	3
BLOOD_Leukemia	UBR1 →	+3.823	+4.430	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,153 associations by consensus.

PIK3R2 by SUPT20H expression — CNS

Explore this box plot interactively →