SUOX

Across TCGA patient cohorts, SUOX protein abundance is significantly associated with the RNA expression of many other genes, with 15,561 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SUOX-associated genes across cancer lineages are MOCS1, JAM2, and CENPM. Each is linked with SUOX in more than 5 cancer types. Because this analysis shows association rather than direction, both SUOX-to-partner and partner-to-SUOX results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SUOX versus MOCS1 in BRCA, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUOX→partner) and Y-score (partner→SUOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MOCS1 →	+1.009	+0.599	<.001	<.001	3	6
BRCA	JAM2 →	+0.704	+0.402	<.001	<.001	3	6
BRCA	CENPM →	-0.702	-0.503	<.001	<.001	3	5
COAD	THBS4 →	+1.350	+0.349	<.001	<.001	3	5
COAD	PDE1A →	+0.714	+0.327	<.001	.001	3	5
HNSC	FILIP1 →	+0.688	+0.311	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,561 associations by consensus.

SUOX vs MOCS1 — BRCA

Explore this scatter interactively →