SUOX

Across TCGA pan-cancer cohorts, SUOX RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SUOX data layer compared with 7 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher SUOX RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SUOX expression acts as an unfavorable survival marker, although some lineages such as KIRP and ACC show a favorable association.

KIRP, ACC, and KIRC are the cancer types where SUOX RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Quartile	II,III,IV	0.813	0.125	.003	59	view →
ACC	DFS	Tertile	III,IV	0.527	0.068	.001	51	view →
KIRC	DFS	Quartile	All	0.733	0.510	<.001	50	view →
SCLC	DFS	Median	II,III,IV	0.833	0.190	<.001	34	view →
BRCA	OS	Tertile	III,IV	0.897	0.729	.001	28	view →
SARC	DFS	Median	All	0.690	0.530	<.001	22	view →
HNSC	DFS	Median	IV	0.710	0.568	.003	21	view →
PAAD	DFS	Tertile	All	0.422	0.184	.018	17	view →
LGG	DFS	Quartile	All	0.680	0.416	.001	16	view →
CHOL	DFS	Median	III,IV	0.127	0.647	.006	15	view →
BLCA	OS	Tertile	All	0.582	0.355	.013	14	view →
MESO	OS	Median	All	0.478	0.312	.020	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SUOX–KIRP (DFS)

Open the KIRP breakdown →