Across TCGA patient cohorts, SUMO3 mutation is significantly associated with the RNA expression of many other genes, with 329 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SUMO3-associated genes across cancer lineages are RPL31P56, RN7SKP77, and RNU6-226P. Each is linked with SUMO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SUMO3-to-partner and partner-to-SUMO3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SUMO3→partner) and Y-score (partner→SUMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RPL31P56 →	+0.240	+2.287	.005	.009	3	2
CESC	RN7SKP77 →	+0.123	+5.837	<.001	.001	3	1
CESC	RNU6-226P →	+0.531	+4.934	<.001	.002	3	1
CESC	PRAMEF19 →	+0.058	+4.812	<.001	.006	3	1
CESC	RNU6-886P →	+0.541	+4.320	<.001	.007	3	1
CESC	RNU6-869P →	+0.464	+5.196	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 329 associations by consensus.

Exploration

SUMO3 survival (RNA) · tumor vs normal (RNA) · all SUMO3 data types