SULT6B1

Across TCGA cell cohorts, SULT6B1 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SULT6B1-associated genes across cancer lineages are OR2AJ1, OR2AK2, and GDF3. Each is linked with SULT6B1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT6B1-to-partner and partner-to-SULT6B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2AJ1 grouped by SULT6B1-low versus SULT6B1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT6B1→partner) and Y-score (partner→SULT6B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR2AJ1 →	+0.006	+5.285	<.001	.003	3	1
STOMACH	OR2AK2 →	+0.063	+5.285	<.001	.003	3	1
BREAST	GDF3 →	+0.135	+5.169	<.001	.005	3	1
LARGE_INTESTINE	EN1 →	+0.831	+3.536	.009	.003	3	1
LARGE_INTESTINE	BPIFB6 →	+0.014	+3.700	<.001	.009	3	1
LARGE_INTESTINE	OR2T33 →	+0.131	+2.845	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

OR2AJ1 by SULT6B1 expression — STOMACH

Explore this box plot interactively →