SULT6B1

Across TCGA pan-cancer cohorts, SULT6B1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of SULT6B1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where SULT6B1 RNA is repressed in tumor relative to normal tissue. In most cancer types SULT6B1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and HNSC are the cancer types where SULT6B1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SULT6B1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−0.053	<.001	7	view →
THCA	Male	All	−0.054	<.001	6	view →
HNSC	All	II,III,IV	+0.017	.017	2	view →
STAD	All	II,III,IV	+0.037	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

SULT6B1–KICH

Open the KICH breakdown →