SULT1E1

Across TCGA cell cohorts, SULT1E1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SULT1E1-associated genes across cancer lineages are P2RY12, CD300H, and IFNA1. Each is linked with SULT1E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SULT1E1-to-partner and partner-to-SULT1E1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, P2RY12 grouped by SULT1E1-low versus SULT1E1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SULT1E1→partner) and Y-score (partner→SULT1E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	P2RY12 →	+0.236	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1
BLOOD_Leukemia	IFNA1 →	+0.180	+5.269	<.001	<.001	3	1
BLOOD_Leukemia	GSG1L2 →	+0.043	+4.969	<.001	.003	3	1
LUNG_NSCLC_LUAD	TEX28 →	+0.006	+5.228	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

P2RY12 by SULT1E1 expression — LARGE_INTESTINE

Explore this box plot interactively →