SULT1E1

Across TCGA pan-cancer cohorts, SULT1E1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated SULT1E1 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in mesothelioma (MESO), where higher SULT1E1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SULT1E1 expression acts as an unfavorable survival marker, although some lineages such as CESC and READ show a favorable association.

MESO, KIRP, and CESC are the cancer types where SULT1E1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.270	0.492	<.001	132	view →
KIRP	DFS	Median	All	0.336	0.765	<.001	120	view →
CESC	OS	Tertile	All	0.900	0.700	<.001	58	view →
PAAD	OS	Median	All	0.515	0.700	.001	39	view →
LGG	DFS	Tertile	All	0.630	0.777	<.001	27	view →
READ	OS	Quartile	III,IV	1.000	0.447	.001	19	view →
CHOL	OS	Median	II,III,IV	0.268	0.974	.003	19	view →
TGCT	DFS	Median	All	0.554	0.788	.001	18	view →
UCS	OS	Median	II,III,IV	0.654	0.357	.019	16	view →
COAD	OS	Median	IV	0.524	0.757	.018	15	view →
THCA	OS	Tertile	II,III,IV	0.907	0.989	.017	10	view →
PRAD	DFS	Tertile	All	0.710	0.827	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

SULT1E1–MESO (OS)

Open the MESO breakdown →