Q-omics provides the consensus-scored SUB1P4 profile across patient tissues and cancer cell-line models. SUB1P4 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, SUB1P4 is differentially expressed in 6, with the highest sampling consensus in KIRP. Additionally, SUB1P4 RNA expression shows 8,623 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight KIRC, KIRP, and GBM as cancer lineages where SUB1P4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SUB1P4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SUB1P4 survival associations across molecular data types. SUB1P4 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SUB1P4 RNA expression–survival associations across cancer types. High SUB1P4 expression shows unfavorable associations in KIRC, ACC and COAD, but favorable associations in SKCM, LUSC and LAML. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for SUB1P4 RNA expression.
This table summarizes SUB1P4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for SUB1P4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SUB1P4 shows higher tumor expression in KIRP, KIRC, COAD, PRAD, LUAD and BLCA. The KIRP box plot shows higher SUB1P4 RNA expression in tumor versus normal tissue (log2 FC = +0.150, t-test p = .014).
This table shows molecular features associated with SUB1P4 in patient tissues and cancer cell lines. In patient samples, SUB1P4 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
