SUB1P4

Across TCGA pan-cancer cohorts, SUB1P4 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated SUB1P4 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher SUB1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SUB1P4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and LUSC show a favorable association.

KIRC, ACC, and SKCM are the cancer types where SUB1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	II,III,IV	0.487	0.772	<.001	125	view →
ACC	OS	Tertile	II,III,IV	0.563	0.911	.001	51	view →
SKCM	DFS	Quartile	III,IV	0.854	0.550	.004	30	view →
LUSC	DFS	Tertile	II,III,IV	0.997	0.631	.003	19	view →
COAD	OS	Tertile	IV	0.315	0.648	.010	9	view →
LAML	DFS	Median	All	0.694	0.440	.012	6	view →
BRCA	DFS	Quartile	III,IV	0.808	0.906	.021	5	view →
DLBC	OS	Tertile	II,III,IV	0.347	0.932	.020	4	view →
LUAD	DFS	Median	III,IV	0.621	0.366	.030	4	view →
CESC	DFS	Quartile	III,IV	0.699	0.259	.043	2	view →
BLCA	DFS	Median	IV	0.474	0.254	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

SUB1P4–KIRC (DFS)

Open the KIRC breakdown →