STX16-NPEPL1

Across TCGA cell cohorts, STX16-NPEPL1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. CNS shows the largest number of these associations.

The most reproducible STX16-NPEPL1-associated genes across cancer lineages are TGM7, ZNF735, and OR4F15. Each is linked with STX16-NPEPL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STX16-NPEPL1-to-partner and partner-to-STX16-NPEPL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM7 grouped by STX16-NPEPL1-low versus STX16-NPEPL1-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STX16-NPEPL1→partner) and Y-score (partner→STX16-NPEPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TGM7 →	+0.013	+5.087	<.001	.004	3	1
CNS	ZNF735 →	+0.487	+5.044	<.001	.001	3	1
LARGE_INTESTINE	OR4F15 →	+0.015	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TGM7 by STX16-NPEPL1 expression — URINARY_TRACT

Explore this box plot interactively →