Across TCGA patient cohorts, STUM mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STUM-associated genes across cancer lineages are COPS8P1, ACTR6P1, and MTND3P16. Each is linked with STUM in more than 1 cancer types. Because this analysis shows association rather than direction, both STUM-to-partner and partner-to-STUM results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STUM→partner) and Y-score (partner→STUM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS8P1 →	+0.158	+3.579	<.001	.002	3	1
SKCM	ACTR6P1 →	+0.044	+7.816	<.001	.008	3	1
COAD	MTND3P16 →	+0.134	+7.741	<.001	.009	3	1
UCEC	RNU6-1318P →	+0.584	+3.943	<.001	.002	3	1
UCEC	RNY4P37 →	+0.497	+3.179	.001	.006	3	1
UCEC	RNA5SP417 →	+0.692	+3.766	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

STUM survival (RNA) · tumor vs normal (RNA) · all STUM data types