STUB1

Across TCGA patient cohorts, STUB1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,765 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STUB1-associated genes across cancer lineages are CIAO3, METRN, and RHBDL1. Each is linked with STUB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both STUB1-to-partner and partner-to-STUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STUB1 versus CIAO3 in BRCA, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STUB1→partner) and Y-score (partner→STUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CIAO3 →	+0.659	+0.509	<.001	<.001	3	7
BRCA	METRN →	+1.370	+0.512	<.001	<.001	3	7
BRCA	RHBDL1 →	+1.226	+0.508	<.001	<.001	3	7
OV	DNAJA3 →	+0.475	+0.406	<.001	<.001	3	6
BRCA	GFER →	+0.485	+0.275	.001	.007	3	6
OV	NDUFB10 →	+0.604	+0.497	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,765 associations by consensus.

STUB1 vs CIAO3 — BRCA

Explore this scatter interactively →