STRAP

Across TCGA patient cohorts, STRAP protein abundance is significantly associated with the RNA expression of many other genes, with 12,498 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STRAP-associated genes across cancer lineages are USP5, FOXM1, and MRPL51. Each is linked with STRAP in more than 6 cancer types. Because this analysis shows association rather than direction, both STRAP-to-partner and partner-to-STRAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRAP versus USP5 in UCEC, with a Pearson correlation of 0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRAP→partner) and Y-score (partner→STRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	USP5 →	+0.891	+0.283	.004	<.001	3	7
UCEC	FOXM1 →	+0.996	+0.212	<.001	.001	3	6
COAD	MRPL51 →	+0.756	+0.299	<.001	<.001	3	6
BRCA	CDCA3 →	+0.974	+0.221	.001	.001	3	6
LSCC	XPOT →	+0.699	+0.176	<.001	<.001	3	6
COAD	RPAP3 →	+0.593	+0.288	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,498 associations by consensus.

STRAP vs USP5 — UCEC

Explore this scatter interactively →