STRAP

Across TCGA cell cohorts, STRAP RNA expression is significantly associated with the go_rna of many other GO terms, with 2,663 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible STRAP-associated GO terms across cancer lineages are DNA replication initiation, Lipid translocation, and Ribosomal small subunit export from nucleus. Each is linked with STRAP in more than 9 cancer types. Because this analysis shows association rather than direction, both STRAP-to-partner and partner-to-STRAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by STRAP-low versus STRAP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STRAP→partner) and Y-score (partner→STRAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.162	+0.761	.001	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Lipid translocation →	-0.087	-0.732	<.001	<.001	3	10
URINARY_TRACT	Ribosomal small subunit export from nucleus →	+0.115	+0.958	.001	<.001	3	10
URINARY_TRACT	Pentose-phosphate shunt →	+0.131	+0.901	<.001	<.001	3	9
BONE	tRNA splicing, via endonucleolytic cleavage and ligation →	+0.085	+0.528	.003	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Nuclear pore organization →	+0.131	+0.732	.008	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,663 associations by consensus.

DNA replication initiation by STRAP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →