STRADB

Across TCGA patient cohorts, STRADB RNA expression is significantly associated with the protein abundance of many other proteins, with 13,589 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STRADB-associated proteins across cancer lineages are CTPS2, SPR, and CKAP4_S26. Each is linked with STRADB in more than 3 cancer types. Because this analysis shows association rather than direction, both STRADB-to-partner and partner-to-STRADB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRADB versus CTPS2 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STRADB→partner) and Y-score (partner→STRADB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CTPS2 →	+0.293	+0.462	<.001	<.001	3	4
BRCA	SPR →	+0.470	+0.640	<.001	<.001	3	4
LUAD	CKAP4_S26 →	-0.688	-0.505	<.001	.001	3	4
PDAC	HNF1B_S49 →	+0.964	+0.286	<.001	.001	3	4
BRCA	TXNDC5 →	-0.486	-0.566	<.001	.004	3	4
BRCA	POU2F2_S55 →	-0.795	-0.772	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,589 associations by consensus.

STRADB vs CTPS2 — HNSC

Explore this scatter interactively →