STRADB

Across TCGA patient cohorts, STRADB mutation is significantly associated with the RNA expression of many other genes, with 2,014 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRADB-associated genes across cancer lineages are LINC02079, RN7SL122P, and RNU6-13P. Each is linked with STRADB in more than 1 cancer types. Because this analysis shows association rather than direction, both STRADB-to-partner and partner-to-STRADB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02079 grouped by STRADB-low versus STRADB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRADB→partner) and Y-score (partner→STRADB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02079 →	+0.067	+2.904	<.001	.009	3	2
SKCM	RN7SL122P →	+0.233	+3.766	<.001	.005	3	2
HNSC	RNU6-13P →	+0.305	+4.025	<.001	.004	3	2
UCEC	DPY19L4P2 →	+0.103	+1.917	<.001	.006	3	2
SKCM	LINC00850 →	+0.032	+4.328	<.001	.007	3	2
UCEC	CCDC163 →	+0.545	+3.475	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,014 associations by consensus.

LINC02079 by STRADB expression — UCEC

Explore this box plot interactively →