STRADB

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, STRADB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,354 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STRADB-associated GO terms across cancer lineages are Negative regulation of bone mineralization involved in bone maturation, Transport along microtubule, and Skin epidermis development. Each is linked with STRADB in more than 7 cancer types. Because this analysis shows association rather than direction, both STRADB-to-partner and partner-to-STRADB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of bone mineralization involved in bone maturation grouped by STRADB-low versus STRADB-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STRADB→partner) and Y-score (partner→STRADB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYNegative regulation of bone mineralization involved in bone maturation →+1.546+0.828<.001.00238
BLOOD_LymphomaTransport along microtubule →+0.035+1.105<.001<.00138
SKINSkin epidermis development →-0.131-0.857.001.00138
URINARY_TRACTMicrotubule-based transport →+0.034+0.940<.001.00337
BREASTNegative regulation of tumor necrosis factor superfamily cytokine production →-0.131-0.954<.001.00228
BREASTNegative regulation of tumor necrosis factor production →-0.126-1.023.001<.00128
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,354 associations by consensus.

Negative regulation of bone mineralization involved in bone maturation by STRADB expression — OVARY

Box plot of Negative regulation of bone mineralization involved in bone maturation in STRADB-low vs STRADB-high samples in OVARY.

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Exploration