STRA8

Across TCGA patient cohorts, STRA8 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,096 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible STRA8-associated GO terms across cancer lineages are tRNA metabolic process, tRNA processing, and Regulation of DNA-directed DNA polymerase activity. Each is linked with STRA8 in more than 12 cancer types. Because this analysis shows association rather than direction, both STRA8-to-partner and partner-to-STRA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA metabolic process grouped by STRA8-low versus STRA8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA8→partner) and Y-score (partner→STRA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	tRNA metabolic process →	+0.048	+0.281	<.001	<.001	3	13
STAD	tRNA processing →	+0.060	+0.357	<.001	.001	3	12
STAD	Regulation of DNA-directed DNA polymerase activity →	+0.083	+0.405	<.001	<.001	3	12
SCLC	Positive regulation of transcription by RNA polymerase I →	+0.097	+0.218	<.001	.009	3	12
STAD	Aerobic respiration →	+0.057	+0.325	<.001	<.001	3	12
STAD	Nucleoside triphosphate biosynthetic process →	+0.056	+0.290	<.001	<.001	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,096 associations by consensus.

tRNA metabolic process by STRA8 expression — STAD

Explore this box plot interactively →