STRA8

Across TCGA patient cohorts, STRA8 protein abundance is significantly associated with the go_rna of many other GO terms, with 5 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible STRA8-associated GO terms across cancer lineages are Embryonic body morphogenesis, Regulation of postsynaptic membrane potential, and Spinal cord oligodendrocyte cell differentiation. Each is linked with STRA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRA8-to-partner and partner-to-STRA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Embryonic body morphogenesis grouped by STRA8-low versus STRA8-high in LUAD.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA8→partner) and Y-score (partner→STRA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	Embryonic body morphogenesis →	+0.057	+2.201	.001	.006	3	1
LUAD	Regulation of postsynaptic membrane potential →	+0.054	+1.315	.005	.007	3	1
LUAD	Spinal cord oligodendrocyte cell differentiation →	+0.272	+2.095	.008	.003	2	1
LUAD	Oxidative demethylation →	+0.086	+2.214	.006	.006	2	1
LUAD	Positive regulation of double-strand break repair via nonhomologous end joining →	+0.050	+2.201	.003	.006	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Embryonic body morphogenesis by STRA8 expression — LUAD

Explore this box plot interactively →