STRA8

Across TCGA cell cohorts, STRA8 RNA expression is significantly associated with the mutation status of many other genes, with 206 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STRA8-associated genes across cancer lineages are KCNA10, BRINP3, and ARHGAP31. Each is linked with STRA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRA8-to-partner and partner-to-STRA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KCNA10 grouped by STRA8-low versus STRA8-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA8→partner) and Y-score (partner→STRA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KCNA10 →	+3.544	+0.431	.009	<.001	3	2
LUNG_NSCLC_LUAD	BRINP3 →	+2.473	+0.183	.003	.001	3	2
LUNG_NSCLC_LUAD	ARHGAP31 →	+3.374	+0.320	.002	<.001	3	2
LARGE_INTESTINE	SAMD3 →	+4.415	+0.161	.007	<.001	3	2
SOFT_TISSUE	FAM135B →	+3.297	+0.016	.008	.001	3	1
SOFT_TISSUE	NAV2 →	+3.882	+0.019	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 206 associations by consensus.

KCNA10 by STRA8 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →