STRA6LP

Across TCGA patient cohorts, STRA6LP mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRA6LP-associated genes across cancer lineages are FASN, Gab2, and Tuberin. Each is linked with STRA6LP in more than 1 cancer types. Because this analysis shows association rather than direction, both STRA6LP-to-partner and partner-to-STRA6LP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by STRA6LP-low versus STRA6LP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA6LP→partner) and Y-score (partner→STRA6LP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.542	+3.169	.012	.020	3	1
UCEC	Gab2 →	+0.674	+3.169	<.001	.020	3	1
UCEC	Tuberin →	+0.299	+2.817	.043	.036	3	1
UCEC	EGFR_pY1068 →	-0.426	-3.169	.001	.020	1	1
UCEC	eIF4G →	+0.475	+3.169	.005	.020	1	1
UCEC	ER-alpha →	-1.067	-3.169	.018	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

FASN by STRA6LP expression — UCEC

Explore this box plot interactively →