STRA6LP

Across TCGA pan-cancer cohorts, STRA6LP RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated STRA6LP data layer compared with 4 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher STRA6LP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STRA6LP expression acts as an unfavorable survival marker, although some lineages such as PAAD and CHOL show a favorable association.

ACC, PAAD, and CHOL are the cancer types where STRA6LP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.491	0.824	<.001	54	view →
PAAD	OS	Tertile	All	0.729	0.521	.001	42	view →
CHOL	OS	Tertile	II,III,IV	1.000	0.222	.005	33	view →
KICH	DFS	Tertile	II,III,IV	0.688	1.000	.013	31	view →
CESC	OS	Quartile	IV	1.000	0.210	.015	30	view →
UCS	DFS	Median	IV	0.909	0.416	.008	30	view →
SKCM	DFS	Median	All	0.325	0.165	.006	28	view →
UVM	OS	Tertile	III,IV	0.484	0.889	.004	25	view →
LUAD	OS	Quartile	All	0.828	0.638	<.001	22	view →
LIHC	DFS	Quartile	II,III,IV	0.543	0.156	<.001	15	view →
PRAD	DFS	Quartile	All	0.657	0.884	.004	12	view →
LUSC	DFS	Median	II,III,IV	0.271	0.447	.007	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

STRA6LP–ACC (DFS)

Open the ACC breakdown →