STON1-GTF2A1L

Across TCGA patient cohorts, STON1-GTF2A1L mutation is significantly associated with the RNA expression of many other genes, with 3,628 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STON1-GTF2A1L-associated genes across cancer lineages are COPS9, MEA1, and MYO19. Each is linked with STON1-GTF2A1L in more than 2 cancer types. Because this analysis shows association rather than direction, both STON1-GTF2A1L-to-partner and partner-to-STON1-GTF2A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPS9 grouped by STON1-GTF2A1L-low versus STON1-GTF2A1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STON1-GTF2A1L→partner) and Y-score (partner→STON1-GTF2A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS9 →	+0.405	+4.021	<.001	<.001	3	3
UCEC	MEA1 →	+0.256	+3.721	.009	<.001	3	3
UCEC	MYO19 →	+0.593	+2.378	<.001	<.001	3	3
UCEC	MIR3661 →	+0.560	+1.671	<.001	.001	3	2
UCEC	ZNF215 →	+0.460	+1.534	.001	.005	3	2
UCEC	CENPU →	+0.801	+2.787	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,628 associations by consensus.

COPS9 by STON1-GTF2A1L expression — UCEC

Explore this box plot interactively →