STON1-GTF2A1L

Across TCGA cell cohorts, STON1-GTF2A1L mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STON1-GTF2A1L-associated genes across cancer lineages are SCGB1D4, XPNPEP2, and HSFY2. Each is linked with STON1-GTF2A1L in more than 1 cancer types. Because this analysis shows association rather than direction, both STON1-GTF2A1L-to-partner and partner-to-STON1-GTF2A1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB1D4 grouped by STON1-GTF2A1L-low versus STON1-GTF2A1L-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STON1-GTF2A1L→partner) and Y-score (partner→STON1-GTF2A1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	SCGB1D4 →	+0.275	+5.169	<.001	.005	3	1
LUNG_NSCLC_LUAD	XPNPEP2 →	+0.136	+4.070	.001	.009	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	GSG1L2 →	+0.026	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SCGB1D4 by STON1-GTF2A1L expression — BREAST

Explore this box plot interactively →