STN1

Across TCGA patient cohorts, STN1 mutation is significantly associated with the RNA expression of many other genes, with 915 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STN1-associated genes across cancer lineages are MIR4276, RNU6-1318P, and CDH12P1. Each is linked with STN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STN1-to-partner and partner-to-STN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4276 grouped by STN1-low versus STN1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STN1→partner) and Y-score (partner→STN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR4276 →	+0.413	+7.954	<.001	.008	3	2
UCEC	RNU6-1318P →	+0.372	+2.899	<.001	.003	3	2
STAD	CDH12P1 →	+0.094	+5.105	<.001	.008	3	2
BRCA	H3P46 →	+0.193	+7.731	<.001	.009	3	1
BRCA	MIR3689D2 →	+0.552	+8.055	<.001	.007	3	1
UCEC	SERPING1 →	-0.839	-3.807	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 915 associations by consensus.

MIR4276 by STN1 expression — HNSC

Explore this box plot interactively →