STN1

Across TCGA pan-cancer cohorts, STN1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of STN1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where STN1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STN1 is over-expressed in tumor, although a few such as HNSC and LUSC show the opposite, repressed pattern.

LIHC, HNSC, and LUSC are the cancer types where STN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	II,III,IV	+1.179	<.001	9	view →
HNSC	All	II,III,IV	−0.482	<.001	8	view →
LUSC	Female	II,III,IV	−0.984	<.001	7	view →
KICH	All	All	−0.609	<.001	6	view →
CHOL	All	All	+1.988	<.001	5	view →
THCA	All	II,III,IV	+0.252	.001	5	view →
BRCA	Female	All	−0.138	.018	3	view →
UCEC	All	All	−0.441	.008	2	view →
KIRP	All	All	−0.231	.011	2	view →
PRAD	All	All	−0.211	.018	2	view →
LUAD	All	All	−0.202	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

STN1–LIHC

Open the LIHC breakdown →