STK17B

Across TCGA patient cohorts, STK17B protein abundance is significantly associated with the RNA expression of many other genes, with 18,133 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STK17B-associated genes across cancer lineages are JAK3, CD7, and ITGAL. Each is linked with STK17B in more than 9 cancer types. Because this analysis shows association rather than direction, both STK17B-to-partner and partner-to-STK17B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STK17B versus JAK3 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK17B→partner) and Y-score (partner→STK17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	JAK3 →	+0.950	+0.437	<.001	<.001	3	10
BRCA	CD7 →	+0.897	+0.448	<.001	<.001	3	10
HNSC	ITGAL →	+0.986	+0.393	<.001	<.001	3	10
UCEC	IL21R →	+1.040	+0.522	<.001	<.001	3	9
UCEC	LILRB1 →	+0.934	+0.382	<.001	.005	3	9
UCEC	IL10RA →	+1.111	+0.533	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,133 associations by consensus.

STK17B vs JAK3 — BRCA

Explore this scatter interactively →