STK17B

Across TCGA cell cohorts, STK17B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,166 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STK17B-associated GO terms across cancer lineages are Regulation of fibroblast apoptotic process, Maintenance of location, and Maintenance of location in cell. Each is linked with STK17B in more than 10 cancer types. Because this analysis shows association rather than direction, both STK17B-to-partner and partner-to-STK17B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of fibroblast apoptotic process grouped by STK17B-low versus STK17B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STK17B→partner) and Y-score (partner→STK17B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of fibroblast apoptotic process →	+0.203	+1.454	<.001	<.001	3	11
OVARY	Maintenance of location →	+0.081	+0.744	<.001	.007	3	10
BREAST	Maintenance of location in cell →	+0.062	+0.783	.004	.005	3	10
UPPER_AERODIGESTIVE_TRACT	Phosphatidylinositol metabolic process →	+0.047	+0.706	.004	.004	2	10
BLOOD_Leukemia	Positive regulation of GTPase activity →	+0.040	+1.059	.001	.001	3	9
LIVER	Xenobiotic transmembrane transport →	-0.181	-1.193	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,166 associations by consensus.

Regulation of fibroblast apoptotic process by STK17B expression — BONE

Explore this box plot interactively →