STK11IP

Across TCGA patient cohorts, STK11IP protein abundance is significantly associated with the RNA expression of many other genes, with 10,771 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STK11IP-associated genes across cancer lineages are CHAF1A, TIPIN, and NCAPG. Each is linked with STK11IP in more than 4 cancer types. Because this analysis shows association rather than direction, both STK11IP-to-partner and partner-to-STK11IP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STK11IP versus CHAF1A in LSCC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK11IP→partner) and Y-score (partner→STK11IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CHAF1A →	-0.710	-0.156	<.001	<.001	3	5
LSCC	TIPIN →	-0.719	-0.210	<.001	<.001	3	5
BRCA	NCAPG →	-0.880	-0.215	<.001	<.001	2	5
LSCC	LMNB1 →	-0.831	-0.226	<.001	<.001	3	4
LSCC	NCL →	-0.349	-0.115	<.001	.002	3	4
LSCC	HELLS →	-0.697	-0.134	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,771 associations by consensus.

STK11IP vs CHAF1A — LSCC

Explore this scatter interactively →