STK11IP

Across TCGA pan-cancer cohorts, STK11IP RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated STK11IP data layer compared with 5 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher STK11IP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STK11IP expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

ACC, HNSC, and LIHC are the cancer types where STK11IP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.245	0.676	<.001	92	view →
HNSC	OS	Tertile	II,III,IV	0.523	0.324	<.001	71	view →
LIHC	OS	Tertile	All	0.589	0.776	<.001	49	view →
LGG	DFS	Median	All	0.278	0.472	<.001	46	view →
PAAD	OS	Tertile	All	0.530	0.285	.004	36	view →
LUSC	DFS	Quartile	III,IV	0.132	0.874	.001	36	view →
STAD	OS	Median	All	0.634	0.487	.003	25	view →
KIRC	DFS	Quartile	IV	0.195	0.489	.005	20	view →
SCLC	OS	Quartile	All	0.684	0.383	.017	18	view →
MESO	DFS	Median	IV	0.178	0.491	.008	18	view →
KICH	DFS	Median	III,IV	0.306	0.882	.010	18	view →
UVM	DFS	Tertile	All	0.395	0.732	.015	16	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

STK11IP–ACC (DFS)

Open the ACC breakdown →