STIL

Across TCGA patient cohorts, STIL protein abundance is significantly associated with the protein abundance of many other proteins, with 26,178 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STIL-associated proteins across cancer lineages are NOP2, RAB3GAP1_S664, and ACBD5_S418. Each is linked with STIL in more than 1 cancer types. Because this analysis shows association rather than direction, both STIL-to-partner and partner-to-STIL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STIL versus NOP2 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STIL→partner) and Y-score (partner→STIL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NOP2 →	+0.759	+1.053	<.001	<.001	3	2
BRCA	RAB3GAP1_S664 →	+0.899	+0.884	<.001	<.001	3	2
HNSC	ACBD5_S418 →	+1.283	+0.875	<.001	.001	3	2
BRCA	RFC1 →	+0.288	+0.728	<.001	<.001	3	1
BRCA	RFC4 →	+0.324	+0.696	<.001	.004	3	1
BRCA	RGL2 →	-0.525	-1.105	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26,178 associations by consensus.

STIL vs NOP2 — BRCA

Explore this scatter interactively →