STAR

Across TCGA cell cohorts, STAR RNA expression is significantly associated with the go_rna of many other GO terms, with 3,826 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STAR-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Protein-DNA complex organization, and mRNA transcription by RNA polymerase II. Each is linked with STAR in more than 7 cancer types. Because this analysis shows association rather than direction, both STAR-to-partner and partner-to-STAR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by STAR-low versus STAR-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STAR→partner) and Y-score (partner→STAR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.077	+0.142	<.001	.001	3	8
BONE	Protein-DNA complex organization →	+0.069	+0.951	<.001	<.001	3	8
BONE	mRNA transcription by RNA polymerase II →	+0.063	+0.879	.001	<.001	3	8
BREAST	Negative regulation of myoblast fusion →	+0.075	+0.142	<.001	.001	3	7
BREAST	Regulation of protein localization to Cajal body →	+0.060	+0.160	<.001	<.001	3	7
BREAST	Positive regulation of protein localization to Cajal body →	+0.060	+0.160	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,826 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by STAR expression — BREAST

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