STAG3L5P

Across TCGA patient cohorts, STAG3L5P mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STAG3L5P-associated genes across cancer lineages are RNU6-974P, DEFT1P, and VCY1B. Each is linked with STAG3L5P in more than 1 cancer types. Because this analysis shows association rather than direction, both STAG3L5P-to-partner and partner-to-STAG3L5P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-974P grouped by STAG3L5P-low versus STAG3L5P-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAG3L5P→partner) and Y-score (partner→STAG3L5P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-974P →	+0.343	+8.471	<.001	.005	3	2
BRCA	DEFT1P →	+1.097	+8.055	<.001	.007	3	2
BRCA	VCY1B →	+0.073	+7.731	<.001	.009	3	1
BRCA	RN7SKP33 →	+0.119	+7.731	<.001	.009	3	1
BRCA	DEFB130D →	+0.178	+8.055	<.001	.007	3	1
BRCA	TSPY19P →	+0.089	+8.055	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

RNU6-974P by STAG3L5P expression — BRCA

Explore this box plot interactively →