STAG3L5P

Across TCGA pan-cancer cohorts, STAG3L5P RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of STAG3L5P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where STAG3L5P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STAG3L5P is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.

HNSC, COAD, and KIRC are the cancer types where STAG3L5P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STAG3L5P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+1.017	<.001	11	view →
COAD	Male	II,III,IV	+1.024	<.001	10	view →
KIRC	Male	II,III,IV	+0.765	<.001	10	view →
LIHC	Female	All	+0.798	<.001	9	view →
STAD	All	II,III,IV	+0.805	.001	7	view →
BLCA	All	All	+0.740	.004	6	view →
LUSC	All	All	+0.587	<.001	4	view →
BRCA	Female	All	−0.315	.013	4	view →
CHOL	All	All	+1.853	<.001	3	view →
READ	Female	All	+1.624	.001	2	view →
ESCA	All	All	+0.806	.015	2	view →
LUAD	All	All	+0.424	.009	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

STAG3L5P–HNSC

Open the HNSC breakdown →