STAC

Across TCGA patient cohorts, STAC RNA expression is significantly associated with the protein abundance of many other proteins, with 16,342 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STAC-associated proteins across cancer lineages are MSN, PTGS1, and S100A4. Each is linked with STAC in more than 6 cancer types. Because this analysis shows association rather than direction, both STAC-to-partner and partner-to-STAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAC versus MSN in GBM, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC→partner) and Y-score (partner→STAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MSN →	+0.484	+1.136	.002	.004	3	7
UCEC	PTGS1 →	+0.875	+0.693	<.001	<.001	3	6
GBM	S100A4 →	+0.631	+0.951	.001	.008	2	6
BRCA	IRF2BP1_S384 →	-0.548	-0.800	<.001	.002	3	5
LUAD	MACF1 →	+0.299	+0.848	<.001	.001	3	5
LUAD	UPP1 →	+0.586	+0.988	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,342 associations by consensus.

STAC vs MSN — GBM

Explore this scatter interactively →