STAC

Across TCGA patient cohorts, STAC protein abundance is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible STAC-associated genes across cancer lineages are DSCAM-IT1, KRT43P, and OR9Q2. Each is linked with STAC in more than 1 cancer types. Because this analysis shows association rather than direction, both STAC-to-partner and partner-to-STAC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STAC versus DSCAM-IT1 in LUAD, with a Pearson correlation of 0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STAC→partner) and Y-score (partner→STAC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	DSCAM-IT1 →	+0.120	+1.237	<.001	.009	3	1
LUAD	KRT43P →	+0.109	+1.237	<.001	.009	3	1
LUAD	OR9Q2 →	+0.046	+1.237	.006	.009	2	1
LUAD	RNA5SP431 →	+0.816	+1.237	.004	.009	2	1
LUAD	RNU4-65P →	+1.295	+1.548	<.001	.004	2	1
LUAD	RNU7-130P →	+1.656	+1.237	.005	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

STAC vs DSCAM-IT1 — LUAD

Explore this scatter interactively →