RNA, U7 small nuclear 130 pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU7-130P profile across patient tissues and cancer cell-line models. RNU7-130P expression is associated with patient survival in 8 of 34 cancer types, with the highest sampling consensus in LAML. Among the 18 cancer types available for tumor–normal comparison, RNU7-130P is differentially expressed in 1, with the highest sampling consensus in THCA. Additionally, RNU7-130P RNA expression shows 7,734 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight LAML, THCA, and COAD as cancer lineages where RNU7-130P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU7-130P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU7-130P survival associations across molecular data types. RNU7-130P RNA expression shows survival associations in the most cancer types (8). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU7-130P RNA expression–survival associations across cancer types. High RNU7-130P expression shows unfavorable associations in LUAD, PAAD, CHOL, KICH and PRAD, but favorable associations in LAML. The LAML Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LAML as the clearest survival context for RNU7-130P RNA expression.
This table summarizes RNU7-130P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU7-130P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU7-130P shows lower tumor expression in THCA. The THCA box plot shows higher RNU7-130P RNA expression in normal versus tumor tissue (log2 FC = −0.060, t-test p = .042).
This table shows molecular features associated with RNU7-130P in patient tissues and cancer cell lines. In patient samples, RNU7-130P shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.
