ST8SIA6

Across TCGA patient cohorts, ST8SIA6 protein abundance is significantly associated with the RNA expression of many other genes, with 49 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ST8SIA6-associated genes across cancer lineages are IL1A, TFCP2L1, and UXS1. Each is linked with ST8SIA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA6-to-partner and partner-to-ST8SIA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST8SIA6 versus IL1A in BRCA, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA6→partner) and Y-score (partner→ST8SIA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL1A →	-0.858	-0.646	.009	.006	3	1
BRCA	TFCP2L1 →	-2.815	-0.475	<.001	.007	3	1
BRCA	UXS1 →	-0.681	-0.621	.007	.007	3	1
BRCA	FAIM2 →	+1.698	+0.535	<.001	.001	3	1
BRCA	CCDC65 →	+1.026	+0.529	.001	.002	3	1
BRCA	MAP3K21 →	-1.649	-0.630	.005	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

ST8SIA6 vs IL1A — BRCA

Explore this scatter interactively →