ST8SIA6

Across TCGA patient cohorts, ST8SIA6 mutation is significantly associated with the RNA expression of many other genes, with 1,486 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST8SIA6-associated genes across cancer lineages are MORF4L2P1, RPS11P1, and RANP7. Each is linked with ST8SIA6 in more than 2 cancer types. Because this analysis shows association rather than direction, both ST8SIA6-to-partner and partner-to-ST8SIA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MORF4L2P1 grouped by ST8SIA6-low versus ST8SIA6-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA6→partner) and Y-score (partner→ST8SIA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	MORF4L2P1 →	+0.069	+4.361	.005	.006	3	3
LIHC	RPS11P1 →	+0.102	+5.544	<.001	.004	3	3
SKCM	RANP7 →	+0.070	+5.328	<.001	.003	3	3
SKCM	RN7SL820P →	+0.303	+4.595	<.001	.004	3	3
BLCA	SSX2B →	+0.186	+4.926	<.001	.002	3	3
READ	POU4F2 →	+0.107	+4.445	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,486 associations by consensus.

MORF4L2P1 by ST8SIA6 expression — READ

Explore this box plot interactively →