ST8SIA6

Across TCGA cell cohorts, ST8SIA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,805 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST8SIA6-associated GO terms across cancer lineages are Regulation of vesicle docking, Regulation of phosphatidylcholine biosynthetic process, and Positive regulation of phosphatidylcholine biosynthetic process. Each is linked with ST8SIA6 in more than 5 cancer types. Because this analysis shows association rather than direction, both ST8SIA6-to-partner and partner-to-ST8SIA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vesicle docking grouped by ST8SIA6-low versus ST8SIA6-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA6→partner) and Y-score (partner→ST8SIA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of vesicle docking →	+0.190	+0.794	.001	.001	2	6
OESOPHAGUS	Regulation of phosphatidylcholine biosynthetic process →	+0.146	+0.323	.003	.009	2	6
OESOPHAGUS	Positive regulation of phosphatidylcholine biosynthetic process →	+0.146	+0.323	.003	.009	2	6
BLOOD_Leukemia	Fatty acid beta-oxidation using acyl-CoA dehydrogenase →	+0.045	+1.160	.001	<.001	3	5
OESOPHAGUS	Vacuolar transport →	+0.062	+0.360	.001	.002	3	5
SKIN	Positive regulation of phospholipid biosynthetic process →	+0.103	+0.498	<.001	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,805 associations by consensus.

Regulation of vesicle docking by ST8SIA6 expression — SKIN

Explore this box plot interactively →