ST8SIA6

Across TCGA cell cohorts, ST8SIA6 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ST8SIA6-associated genes across cancer lineages are C6orf118, OR5C1, and SLC32A1. Each is linked with ST8SIA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA6-to-partner and partner-to-ST8SIA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by ST8SIA6-low versus ST8SIA6-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA6→partner) and Y-score (partner→ST8SIA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C6orf118 →	+0.064	+4.450	<.001	.001	3	2
LARGE_INTESTINE	OR5C1 →	+0.044	+3.793	<.001	.007	3	2
BLOOD_Leukemia	SLC32A1 →	+0.904	+3.901	<.001	.006	3	1
BLOOD_Leukemia	IL17F →	+0.044	+3.855	.002	.007	3	1
BLOOD_Leukemia	GZMK →	+0.701	+4.037	<.001	.004	3	1
BLOOD_Leukemia	PAX1 →	+0.029	+4.060	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

C6orf118 by ST8SIA6 expression — BLOOD_Leukemia

Explore this box plot interactively →