ST8SIA3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ST8SIA3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,558 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ST8SIA3-associated genes across cancer lineages are PDE10A, PDE1A, and DYNC1I1. Each is linked with ST8SIA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA3-to-partner and partner-to-ST8SIA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST8SIA3 versus PDE10A in PDAC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA3→partner) and Y-score (partner→ST8SIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACPDE10A →+0.632+0.642.003.00332
GBMPDE1A →+0.838+0.442<.001<.00132
GBMDYNC1I1 →+1.517+0.588<.001<.00132
GBMELAPOR2 →+1.210+0.485<.001<.00132
GBMNAP1L5 →+0.538+0.578<.001<.00132
GBMRPRML →+0.761+0.358<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,558 associations by consensus.

ST8SIA3 vs PDE10A — PDAC

Per-sample scatter of ST8SIA3 vs PDE10A in PDAC (Pearson r = 0.85).

Explore this scatter interactively →

Exploration