ST8SIA3

Across TCGA patient cohorts, ST8SIA3 mutation is significantly associated with the RNA expression of many other genes, with 4,187 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ST8SIA3-associated genes across cancer lineages are RN7SL134P, GLRX5, and UQCR10. Each is linked with ST8SIA3 in more than 3 cancer types. Because this analysis shows association rather than direction, both ST8SIA3-to-partner and partner-to-ST8SIA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by ST8SIA3-low versus ST8SIA3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA3→partner) and Y-score (partner→ST8SIA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.077	+1.555	.002	.008	3	4
UCEC	GLRX5 →	+0.282	+2.321	.004	<.001	3	3
UCEC	UQCR10 →	+0.273	+2.169	.001	<.001	3	3
UCEC	UBE2F →	+0.282	+1.468	<.001	.001	3	3
UCEC	UBE2L3 →	+0.323	+1.653	<.001	<.001	3	3
UCEC	RANBP1P1 →	+0.396	+1.869	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,187 associations by consensus.

RN7SL134P by ST8SIA3 expression — UCEC

Explore this box plot interactively →