ST8SIA2

Across TCGA patient cohorts, ST8SIA2 protein abundance is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST8SIA2-associated genes across cancer lineages are TIMM9, CLEC2B, and HTRA2. Each is linked with ST8SIA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA2-to-partner and partner-to-ST8SIA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST8SIA2 versus TIMM9 in LSCC, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA2→partner) and Y-score (partner→ST8SIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TIMM9 →	+0.653	+0.803	.005	<.001	3	1
LSCC	CLEC2B →	-2.356	-0.803	.008	<.001	3	1
LSCC	HTRA2 →	+1.326	+0.743	.003	.003	3	1
LSCC	IRF2BPL →	+1.359	+0.709	.008	.008	3	1
LSCC	FLRT1 →	+1.290	+0.803	.001	<.001	3	1
LSCC	EPSTI1 →	-1.646	-0.743	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 81 associations by consensus.

ST8SIA2 vs TIMM9 — LSCC

Explore this scatter interactively →