ST8SIA2

Across TCGA cell cohorts, ST8SIA2 mutation is significantly associated with the RNA expression of many other genes, with 74 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ST8SIA2-associated genes across cancer lineages are KDELR3, TMEM147, and CHN2. Each is linked with ST8SIA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ST8SIA2-to-partner and partner-to-ST8SIA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KDELR3 grouped by ST8SIA2-low versus ST8SIA2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA2→partner) and Y-score (partner→ST8SIA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KDELR3 →	+1.377	+3.502	<.001	.001	3	1
LARGE_INTESTINE	TMEM147 →	+0.389	+3.502	.006	.001	3	1
LARGE_INTESTINE	CHN2 →	-1.131	-3.416	.001	.002	3	1
LARGE_INTESTINE	ATPAF1 →	+0.599	+3.502	.002	.001	3	1
LARGE_INTESTINE	ARHGEF9 →	-0.885	-3.087	.004	.007	3	1
LARGE_INTESTINE	ARGLU1 →	-1.001	-3.416	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 74 associations by consensus.

KDELR3 by ST8SIA2 expression — LARGE_INTESTINE

Explore this box plot interactively →