ST8SIA1

Across TCGA cell cohorts, ST8SIA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,235 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ST8SIA1-associated GO terms across cancer lineages are Substantia nigra development, Neural nucleus development, and Purine nucleoside diphosphate catabolic process. Each is linked with ST8SIA1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ST8SIA1-to-partner and partner-to-ST8SIA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Substantia nigra development grouped by ST8SIA1-low versus ST8SIA1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ST8SIA1→partner) and Y-score (partner→ST8SIA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Substantia nigra development →	+0.104	+0.911	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Neural nucleus development →	+0.084	+0.777	<.001	.004	3	7
LIVER	Purine nucleoside diphosphate catabolic process →	+0.112	+1.362	.001	.003	3	6
LIVER	Purine ribonucleoside diphosphate catabolic process →	+0.112	+1.362	.001	.003	3	6
LUNG_NSCLC_LUAD	Host-mediated perturbation of viral genome replication →	+0.075	+0.828	<.001	.002	3	6
BREAST	Positive regulation of viral process →	+0.063	+1.461	.007	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,235 associations by consensus.

Substantia nigra development by ST8SIA1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →