ST6GALNAC6

Across TCGA patient cohorts, ST6GALNAC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,646 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ST6GALNAC6-associated proteins across cancer lineages are TESPA1_S311, EVL, and ANKRD44. Each is linked with ST6GALNAC6 in more than 6 cancer types. Because this analysis shows association rather than direction, both ST6GALNAC6-to-partner and partner-to-ST6GALNAC6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ST6GALNAC6 versus TESPA1_S311 in HNSC, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ST6GALNAC6→partner) and Y-score (partner→ST6GALNAC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TESPA1_S311 →	+0.992	+0.367	<.001	.002	3	7
HNSC	EVL →	+0.807	+0.438	<.001	<.001	3	7
LSCC	ANKRD44 →	+0.345	+0.286	<.001	<.001	3	7
HNSC	PRKCB →	+0.576	+0.312	<.001	.001	3	6
HNSC	PTPN7 →	+0.532	+0.362	<.001	<.001	3	6
HNSC	PYHIN1 →	+1.036	+0.446	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,646 associations by consensus.

ST6GALNAC6 vs TESPA1_S311 — HNSC

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